Laboratory Testing
Dr. Kelley offers a variety of laboratory testing and interpretation. Blood Nutrition Analysis information can be found on the "services" page. Other laboratory testing can be found on this page.
Test kits are either given to you in office to take home for sample collection or stop by to pick up a requisition form to take to the lab.
Great Plains Laboratory:
The Great Plains Laboratory, Inc. is a world leader in providing testing for metabolic, genetic, mitochondrial, and environmental factors in chronic illnesses. We offer a variety of state-of-the-art metabolic and genetic tests such as:
the Organic Acids Test (OAT)- Nutritional & Metabolic Profile: Provides an accurate evaluation of intestinal yeast and bacteria. Abnormally high levels of these microorganisms can cause or worsen behavior disorders, hyperactivity, movement disorders, fatigue and immune function. Many people with chronic illnesses and neurological disorders often excrete several abnormal organic acids. The cause of these high levels could include: oral antibiotic use, high sugar diets, immune deficiencies, and genetic factors. If abnormalities are detected, treatments can include supplements, such as vitamins and antioxidants, or dietary modification. Upon treatment, patients and practitioners have reported significant improvement such as decreased fatigue, regular bowel function, increased energy and alertness, increased concentration, improved verbal skills, less hyperactivity, and decreased abdominal pain. The OAT is strongly recommended the initial screening test.
GPL-TOX (Toxic Organic Chemical Profile) -
Every day, we are exposed to hundreds of toxic chemicals through products like pharmaceuticals, pesticides, packaged foods, household products, and environmental pollution. As we have become more accustomed to chemical-laden products, and as our environment has become more contaminated, we have been confronted with an accelerating rate of chronic illnesses like cancer, heart disease, chronic fatigue syndrome, chemical sensitivity, autism spectrum disorders, ADD/AD(H)D, autoimmune disorders, Parkinson's disease, and Alzheimer's disease.
Because exposure to environmental pollutants has been linked to many chronic diseases, The Great Plains Laboratory has created GPL-TOX, a toxic organic exposure profile that screens for the presence of 168 different toxic chemicals including organophosphate pesticides, phthalates, benzene, xylene, vinyl chloride, pyrethrin insecticides, and others. This profile also includes Tiglyglycine (TG), a marker for mitochondrial disorders resulting from mutations of mitochondrial DNA. These mutations can be caused by exposure to toxic chemicals, infections, inflammation, and nutritional deficiencies.
IgG Food Allergies Test
GPL-SNP1000 - DNA Sequencing Profile
The Great Plains Laboratory is excited to announce our brand new genetics test, GPL-SNP1000. This test is the most comprehensive test for alterations in the genetic code in the pathways that are most important for integrative medicine. This test looks at nine core groups of genes which are crucial for many different biological pathways. Previous to GPL-SNP1000, most genetic tests have only looked at a small subset of genes and very few SNPs (single-nucleotide polymorphisms). GPL-SNP1000 includes over 1,000 different SNPs and over 144 different genes. For example, Dr. Amy Yasko’s Nutrigenomics Test includes just 30 SNPs over 13 genes. Our cost per SNP is just $00.67 versus $16.50.
The GPL-SNP1000 will help you determine your predisposition for developing various disorders, including:
ADHD, adverse drug reactions, allergies, anxiety, arthritis, autism spectrum disorders, bipolar disorder, cancer, depression, heart disease, osteoporosis, oxidative stress, and schizophrenia to name a few.
Here are the pathways that GPL-SNP1000 assesses:
- DNA Methylation - critical role in nucleotide synthesis, detoxification, neurotransmitter function and proper cellular function
- Oxalate Metabolism- The degree to which and individual is predisposed to having adverse consequences from high levels of oxalate is influenced by their ability to metabolize oxalates. Deposition of oxalates in critical tissues such as brain and blood vessels, and the oxidative damage caused by oxalate salts can lead to pain, kidney stones and possibly neurological symptoms.
- Mental Disorders / SAM-E/B12 Metabolism- Mutations to these genes can cause an increased risk of developing depression, schizophrenia, anxiety, and bipolar disorder.
- Gluten Opioid Peptide Homeostasis- Mutations in these genes could lead to gluten sensitivity which can manifest in a variety of symptoms. Many patients with autism spectrum disorder report neurological benefits upon switching to a gluten-free diet.
- Autism Spectrum Genes
- P450s (cyps)- Mutations in these genes could alter the appropriate dosage for many medications and could have long-term health consequences. These genes are in a family of enzymes that detoxify endogenous chemicals (including medical drugs) and they metabolize endogenous chemicals including hormones, neurotransmitters, cholesterol, and vitamins.
- Cholesterol Deficiency (synthesis, absorption/transportation)- Low cholesterol values are associated with manganese deficiency, celiac disease, hyperthyroidism, liver disease, malabsorption, and malnutrition.
- Acetaminophen Toxification/Detoxification
- Transporters- Transport proteins are important for shuttling molecules across cellular membranes. Mutations to transporter genes impede the ability of cells to uptake vital nutrients and export toxic substances. Just a few of the diseases associated with faulty transport are Alzheimer's disease, coronary artery disease, aggessive behavior, and decreased drug efficacy.
Diagnos Techs:
The Adrenal Stress Index Panel (ASI) is a simple non-invasive test utilizing four saliva samples collected a specified time periods during the day. It was introduced by Diagnos-Techs in 1989 to evaluate stress, a leading cause of morbidity and mortality.
The Bone Health Panel (BHP) provides an assessment of bone health utilizing a combination of non-invasive saliva and urine tests. It measures how fast bone is being lost and and the hormone levels associated with bone health.
The Female Hormone Panel (FHP) is a non-invasive test consisting of eleven saliva specimens collected during specified time periods throughout the menstrual cycle. The expanded Female Hormone Panel (eFHP) includes fourteen additional measurements.
Food Allergy (Sensitivity) Panel)
The Food Allergy (Sensitivity) Panel tests for an immune response to four of the most common food allergens: gluten, soy, milk, and egg proteins. Antibodies to these foods can easily be tested for from a non-invasive saliva sample, providing information that can aid in successful treatment.
The Gastrointestinal Health Panels (GI) are a group of non-invasive screens of the gastrointestinal tract and its function. It includes 12-22 individual, yet related, tests. Stool and saliva samples are submitted by the patient after home collection.
The Male Hormone Panel (MHP) uses non-invasive testing to assess hormone imbalances and deficiencies in men. Using a saliva sample, seven hormones are measured. The expanded panel adds two more hormone tests to the panel.
The Postmenopausal Panel (PostM) provides measurements of six key hormones. The Perimenopause Panel (PeriM) contains the same components as the Postmenopause Panel but is samples twice, 13-15 days apart. The expanded versions add two more hormones to each panel.
GI Microbial Assay Plus
GI-MAP™
UNCOVER THE UNDERLYING CAUSE OF CHRONIC ILLNESS
Modern technology has given us a number of insights into the root causes of chronic illness. Nowhere has this insight been more revolutionary and impactful than in the human gastrointestinal (GI) tract. The GI tract is home to an entire ecosystem of microorganisms (known as the microbiome), living in a symbiotic relationship with its host. These microorganisms do far more than just reside within us - they are essential for life and health. They are responsible for many important functions such as vitamin synthesis, hormone production, immune system regulation, and communication with the neurological system. More than ever before, medical research has established a link between health benefits or disease risks brought about by these microorganisms that inhabit the human body.
In the last few decades, DNA analysis has transformed the field of microbiology. Almost all research of microbes utilize DNA methodology. The NIH has followed suit with initiatives including the Human Microbiome Project, which characterized the microbiome of 15 habitats of the body using DNA analysis.
More than ever before, we are keenly aware of the health benefits or disease risks brought about by the microorganisms that inhabit the human body. Culture techniques, previously the standard, left up to 50% of bacterial species virtually invisible. Because most of the bacteria of the GI tract are anaerobes, culture based methods cannot cultivate them which leaves a large blind spot for clinicians when trying to diagnose the source of infection.
Diagnostic Solutions Laboratory is pleased to partner with you to bring true ADVANCES in microbial testing. Our commitment to laboratory medicine is to utilize proven methodologies that are accurate and reliable. We are pleased to offer clinicians the first of many advances, the GI-MAP™ (GI Microbial Assay Plus).
GI-MAP™ Advantages
- True DNA/PCR Assay
- Rapid TAT – Results in 3-7 days!
- Quantitative PCR Pathogen Testing
- High Sensitivity and Specificity
- Antibiotic Resistance Genes
- Virulence Factors
The GI-MAP stool test utilizes cutting edge, Quantitative PCR technology to provide a true DNA/PCR based stool test. This technology has high sensitivity, specificity and a rapid turnaround. The GI pathogens include bacteria, parasites and viruses.
Diagnostic Solutions uses the latest and most advanced DNA testing to assess:
- Levels of healthy bacteria
- Pathogenic bacteria
- Parasites
- Yeast
- Viruses
And advanced metabolic testing for:
- Inflammation
- Immune function
- Disgestion and absorption
Continuing with this platform, the GI-MAP measures opportunistic organisms, normal flora, fungi, parasites and antibiotic resistance genes. And the Plusrefers to immunologic markers for GI health and function including SIgA, Elastase, Calprotectin and Anti-gliadin testing.
SCHEDULE A CONSULTATION WITH DR. LEA KELLEY TODAY! (310)545-6528
Flex C
Flexustomized Test Panels
The Male THormone Panel (MHP) uses non-invasive testing to assess hormone imbalances and deficiencies in men. Using a saliva sample, seven hormones are measured. The expanded panel adds two more hormone tests to the panel.
The Gastrointestinal Health Panels (GI) are a group of non-invasive screens of the gastrointestinal tract and its function. It includes 15-22 individual, yet related, tests. Stool and saliva samples are submitted by the patient after home collection
The Food Allergy (Sensitivity) Panel tests for an immune response to four of the most common food allergens: gluten, soy, milk and egg proteins. Antibodies to these foods can easily be tested for from a non-invasive saliva sample, providing information that can aid in successful treatment.
The Female Hormone Panel (FHP) is a non-invasive test consisting of eleven saliva specimens collected during specified time periods throughout the menstrual cycle. The expanded Female Hormone Panel (eFHP) includes fourteen additional measurements.
The Bone Health Panel (BHP) provides an assessment of bone health utilizing a combination of non-invasive saliva and urine tests. It measures how fast bone is being lost and the hormone levels associated with bone health.
The Adrenal Stress Index (ASI) panel is a simple non-invasive test utilizing four saliva samples collected at specified time periods during the day. It was introduced by Diagnos-Techs in 1989 to evaluate stress, a leading cause of morbidity and mortality.